Relation between ambulatory blood pressure variation and heart rate variability in elderly patients with coronary heart disease

Objective To study the influencing factors for blood pressure variability(BPV)in elderly patients with coronary heart disease(CHD)by investigating the relation between ambulatory blood pressure variation(ABPV)and heart rate variability(HRV).Methods One hundred and seventy-nine CHD patients who underwent coronary angiography,24hambulatory blood pressure monitoring(ABPM)and 24hambulatory electrocardiogram were included in this study.Baseline values of coronary angiography,24hABPM,24hambulatory electrocardiogram and other clinical variables were recorded.The patients were divided into dipping group(n=30),non-dipping group(n=84)and anti-dipping group(n=65)according to their circadian rhythym of blood pressure. Their Gensini score and HRV were compared.Results The Gensini score of CHD was higher while the 24hSDNN and SDNNM were lower in non-dipping group and anti-dipping group than in dipping group(P0.05).The 24BPV was not significantly related with the HRV.Conclusion CHD is severer in elderly patients with abnormal circadian rhythym of blood pressure than in those with normal circadian rhythym of blood pressure.The circadian rhythym of blood pressure is related with the HRV which reduces with the circadian rhythym of blood pressure.The BPV measured by ABPM is not significantly related with the HRV.