Comparability analysis and bias evaluation on results of TSH measured at different detection systems

Objective:To explore and evaluate the comparability and bias of the results of TSH measured in two different immune luminescence analysis systems.Methods:According to the U.S.Committee for Clinical Laboratory Standards(NCCLS) EP9-A2,9 clinic samples were detected in two kinds of different analysis systems(Siemens Immulite2000 and Roche E170) respectively everyday.The testing results of total 45 samples were recorded within 5 days.The testing results derived from two analysis systems were analyzed comparatively and their biases were evaluated.Results:The TSH results between the two detection systems were significantly different(P0.01),but the correlation between them was good.The regression equation was y=0.9639x+0.0453,R2=0.998.Use Siemens Immulite2000 analysis system as a control method,the TSH anticipated bias of Roche E170 was within allowed biases,which was acceptable by clinic.Conclusion:The TSH results between the two detection systems were significantly different,but it can be accepted by clinic.