Results comparison and bias estimation between two different biochemical detection systems for serum lipid level

Objective To investigate the results comparability of AU5400 and AU2700 biochemical analysis system for the detection of serum lipids.Methods According to document EP9-A2 of Clinic and Laboratory Standard Institute(CLSI) and taking the half of the allowed total error of Clinical Laboratory Improvement Amendment 88(CLIA′88) as clinically acceptable criterion,the comparability of these two systems for the detection of serum lipids was evaluated.Results There was fine correlation between the detection results of these two systems(r0.975) and the bias was consistent with requirements of CLIA′88.Conclusion Comparative test and bias evaluation of the detected results of the same tests should be performed between different analytical systems,thus to ensure the comparability among test results.