2002•Shanxi Journal of Traditional Chinese MedicineRequires access

Experimental Research on the Effect of Heluoshugan Capsule(和络舒肝胶囊)on Liver Injury

Wen Yang

Abstract

Objective:To observe the effect of Heluoshugan Capsule(HC) on liver injury caused by hepatitis.Methods:The mouse models of acute liver injury were made by 0.1% CCl 4 and solution of vegetable seeds oil and TAA 50mg/kg ip.The models of chronic liver injury and hepatocirrhosis were made by 40% CCl 4 and solution of plant oil 5.0ml/kg subcutaneously in the back of rats for 6 weeks.The blood ALT?pathological changes of the liver and collagen were observed.Results:Heluohshugan Capsule could control the high ALT in acute liver injury.It could also reduce the liver collagen in chronic liver injury and hepatocirrhosis.Conclusion:Heluoshugan capsule had preventive and therapeutic effect on experimental acute or chronic liver injury.

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Key concepts: Medicine, Capsule, Liver injury, Pathological, Chronic hepatitis, Acute injury, Internal medicine, Gastroenterology