Study on Therapeutic Function of Ganyanling on Experimental Chronic Liver Injury

Objective To observe the therapeutic action of Gangyanling on experimental chronic liver injury.Methods The models of chronic liver injury in rats were set up with CCl 4,and 7 weeks later treated with Ganyanling both by ig or ip for 12 weeks.Results Use of Ganyanling by ig or ip was able to decrease ALT,AST and liver hydroxyproline levels in chronic injury rats,and increase the serum albumin level and the ratio of A/G.Histology examination indicates that Ganyanling was able to lessen degeneration and necrosis of liver cells,and inhibit the proliferation of fibrous tissue in liver.Conclusion Ganyanling given by ig or ip both can relieve the degree of chronic liver injury,which has the function to reduce the harm of free radical to liver cells and the function of anti-fibrosis in liver.