Infection Survey and Drug-resistance Analysis of Acinetobacter Baumannii
Zhu Wei-gu
Abstract
Zhu Wei-gu
Abstract
Objective To investigate the clinical distribution and drug sensitivity of Acinetobacter baumannii infection.Methods Microbial samples sent to our department for examination from January 2009 to December 2011 were statistically analyzed.Nineteen strains of Acinetobacter baumannii were cultured in 2009,29 in 2010(including 1 multi-drug-resistant strain),and 35 in 2011(including 2 multi-drug-resistant strains).The distribution of specimen type,departments and drug resistance was analyzed.Results The highest detection rate of Acinetobacter baumannii was found in sputum.Departments with high to low detection rate were respectively ICU,neurosurgery,and respiratory department.The bacteria was most sensitive to imipenem.The resistance rate to penicillin and cephalosporin were above 55%.Conclusions For patients with Acinetobacter baumannii infection,empiric antibiotics should be selected appropriately based on nosocomial infection distribution and drug resistance of pathogens in the local region and hospitals.The disease condition,old age,immunosuppressive agents,mechanical ventilation,a variety of invasive operations and antibiotic use are risk factors for nosocomial infection of Acinetobacter baumannii.ICU has the presence of multiple drug-resistant Acinetobacter baumannii infection,which should be controlled.
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Objective To investigate the clinical distribution and drug sensitivity of Acinetobacter baumannii infection.Methods Microbial samples sent to our department for examination from January 2009 to December 2011 were statistically analyzed.Nineteen strains of Acinetobacter baumannii were cultured in 2009,29 in 2010(including 1 multi-drug-resistant strain),and 35 in 2011(including 2 multi-drug-resistant strains).The distribution of specimen type,departments and drug resistance was analyzed.Results The highest detection rate of Acinetobacter baumannii was found in sputum.Departments with high to low detection rate were respectively ICU,neurosurgery,and respiratory department.The bacteria was most sensitive to imipenem.The resistance rate to penicillin and cephalosporin were above 55%.Conclusions For patients with Acinetobacter baumannii infection,empiric antibiotics should be selected appropriately based on nosocomial infection distribution and drug resistance of pathogens in the local region and hospitals.The disease condition,old age,immunosuppressive agents,mechanical ventilation,a variety of invasive operations and antibiotic use are risk factors for nosocomial infection of Acinetobacter baumannii.ICU has the presence of multiple drug-resistant Acinetobacter baumannii infection,which should be controlled.
Key concepts: Acinetobacter baumannii, Medicine, Imipenem, Drug resistance, Penicillin, Microbiology, Antibiotics, Acinetobacter