Effect of hyponatremia on liver function grade and prognosis of decompensated cirrhosis cases

Objective To explore the relationship between hyponatremia and liver function grade and prognosis of decompensated cirrhosis cases.Methods One hundred and sixty-two decompensated cirrhosis cases with hyponatremia were analyzed retrospectively,according to their serum sodium levels,the patients were divided into mild,moderate and severe hyponatremia groups,and the Child-pugh grade,the incidence were compared among the main complications and case fatality rate of these three groups.Results Child-pugh grades of the mild group,the moderate group and the severe group were 6.86±1.45,7.98±1.69 and 9.96±2.23 respectively,the more serious of the degree of hyponatremia was,the higher the score was(P0.01);the main complications,hepatic encephalopathy,hepatorenal syndrome,hypopotassaemia and the incidence of refractory ascites,increased with the worse of hyponatremia.The differences were statistical significant among the three groups(P0.01 or P0.05);case fatality rates of the mild group,the moderate group and the severe group were 3.92%,19.72% and 60.00% respectively,case fatality rates had significant differences among the three groups(P0.05).Conclusion To some degree,hyponatremia reflected the damaged condition of liver function of decompensated cirrhosis cases.The serum sodium level in decompensated cirrhosis cases can be used as an important indicator to detect the disease severity.