Study on the Relationship Between Hyponatremia and Severity of the Diseases in DecompensationCirrhosis

Objective To explore the relationship between different serum sodium level and severity of the diseases in decompensation cirrhosis patients.Methods 145 cirrhosis ascites patietns with hyponatremia were analyzed retrospectively.The patients were divided into mild,moderate and severe hyponatremia groups according to their serum sodium levels and graded with MELD formula and Child-Pugh respectively,their complications and prognosis were observed.Results The more severe patients' hyponatremia,the higher their MELD and Child-Pugh scores.There were significantly different in MELD and Child-Pugh scores among the three groups(P0.01).The severe hyponatremia group was significantly higher than the moderate and low hyponatremia groups in hepatic encephalopathy,hepatorenal syndrome,hypokalemia,refractory ascites incidence and mortality(P0.05,P0.01),the moderate hyponatremia group was also significantly higher than the lower one in hepatic encephalopathy,refractory ascites incidence and mortality(P0.05,P0.01).Conclusion The levels of serum sodium for decompensation cirrhosis patients are interrelations to the severity of their condition,monitoring of serum sodium levels can be used as one of important indicators to determine the extension of severity in patients with cirrhotic ascites.