Distribution and antibiotic resistance of pathogenic bacteria isolated from inpatients

Objective To investigate the distribution and antibiotic resistance of clinical bacteria isolated from inpatients in our hospital.Methods Bacterial identification and antibiotic susceptibility testing were carried out using MicroScanAutoScan-40 system. ESBLs production was also determined.Results A total of 614 clinical isolates were analyzed,including 90 strains of gram-positive cocci and 524 strains of gram-negative bacilli. The prevalence of methicillin-resistant S. aureus and methicillin-resistant coagulase-negative Staphylococcus was 30.3% and 35.3% respectively. No vancomycin-resistant Staphylococcus or Enterococcus strain was identified. ESBLs-producing strains accounted for 62.5 % of E. coli and 32 % of Klebsiella. The gram-negative bacilli strains were highly resistant to antimicrobial agents (except imipenem).Conclusions It is important to prescribe antibiotics rationally and monitor the antimicrobial resistance of clinical pathogens.