2009PubMedRequires access

[Studies on the chemical constituents of Phellodendron chinense].

Meng Wang, Tengfei Ji, Jianbo Yang, Ya‐Lun Su

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Abstract

OBJECTIVE: To isolate and identify chemical constituents from Phellodendron chinense. METHODS: Chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatography. The structures of the isolated compounds were determined by spectral means. RESULTS: Ten compounds were isolated and identified as berberine (1), caffeic acid ethyl ester (2), iso-vanillin (3), ferulic acid (4), (+/-)-5,5'-dimethoxylariciresinol (5), Methyl beta-orsellinate (6), gamma-fagirine (7), (+/-)-Lyoniresinol (8), beta-sitosterol (9), stigmasterine (10). CONCLUSIONS: Compounds 2-6 are isolated and identified from this genus for the first time.

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What this paper is about

OBJECTIVE: To isolate and identify chemical constituents from Phellodendron chinense. METHODS: Chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatography. The structures of the isolated compounds were determined by spectral means. RESULTS: Ten compounds were isolated and identified as berberine (1), caffeic acid ethyl ester (2), iso-vanillin (3), ferulic acid (4), (+/-)-5,5'-dimethoxylariciresinol (5), Methyl beta-orsellinate (6), gamma-fagirine (7), (+/-)-Lyoniresinol (8), beta-sitosterol (9), stigmasterine (10). CONCLUSIONS: Compounds 2-6 are isolated and identified from this genus for the first time.

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Available abstract

OBJECTIVE: To isolate and identify chemical constituents from Phellodendron chinense. METHODS: Chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatography. The structures of the isolated compounds were determined by spectral means. RESULTS: Ten compounds were isolated and identified as berberine (1), caffeic acid ethyl ester (2), iso-vanillin (3), ferulic acid (4), (+/-)-5,5'-dimethoxylariciresinol (5), Methyl beta-orsellinate (6), gamma-fagirine (7), (+/-)-Lyoniresinol (8), beta-sitosterol (9), stigmasterine (10). CONCLUSIONS: Compounds 2-6 are isolated and identified from this genus for the first time.

Key concepts: Berberine, Sephadex, Chemistry, Chemical constituents, Vanillin, Caffeic acid, Silica gel, Ferulic acid

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