2013Zhongguo shiyan fangjixue zazhiRequires access

Study on Chemical Constituents from Phellodendron chinense

Lian Lia

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Abstract

Objective: To isolate and identify chemical constituents from Phellodendron chinense.Method: Compounds were isolated by silica gel and Sephadex LH-20 column chromatography,and their structures were determined by means of the spectral analysis and physicochemical properties. Result: Eleven compounds were isolated and identified as berberine( 1),obaculactone( 2),shihulimoninA( 3),N-p-coumaroyltyramine( 4),1-( 4-hydroxy-3-methoxyphenyl)-2-[4-( 3-hydroxy-propyl)-2-methoxyphenoxy]-propane-1,3-diol( 5),phellodendrine( 6),magnoflorine( 7),palmatine( 8),jatrorrhizine( 9),columbamine( 10),obacunone( 11). Conclusion: Compounds 3 and 5 were isolated from P. genus for the first time,and compound4 was isolated from this plant for the first time.

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Objective: To isolate and identify chemical constituents from Phellodendron chinense.Method: Compounds were isolated by silica gel and Sephadex LH-20 column chromatography,and their structures were determined by means of the spectral analysis and physicochemical properties. Result: Eleven compounds were isolated and identified as berberine( 1),obaculactone( 2),shihulimoninA( 3),N-p-coumaroyltyramine( 4),1-( 4-hydroxy-3-methoxyphenyl)-2-[4-( 3-hydroxy-propyl)-2-methoxyphenoxy]-propane-1,3-diol( 5),phellodendrine( 6),magnoflorine( 7),palmatine( 8),jatrorrhizine( 9),columbamine( 10),obacunone( 11). Conclusion: Compounds 3 and 5 were isolated from P. genus for the first time,and compound4 was isolated from this plant for the first time.

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Available abstract

Objective: To isolate and identify chemical constituents from Phellodendron chinense.Method: Compounds were isolated by silica gel and Sephadex LH-20 column chromatography,and their structures were determined by means of the spectral analysis and physicochemical properties. Result: Eleven compounds were isolated and identified as berberine( 1),obaculactone( 2),shihulimoninA( 3),N-p-coumaroyltyramine( 4),1-( 4-hydroxy-3-methoxyphenyl)-2-[4-( 3-hydroxy-propyl)-2-methoxyphenoxy]-propane-1,3-diol( 5),phellodendrine( 6),magnoflorine( 7),palmatine( 8),jatrorrhizine( 9),columbamine( 10),obacunone( 11). Conclusion: Compounds 3 and 5 were isolated from P. genus for the first time,and compound4 was isolated from this plant for the first time.

Key concepts: Palmatine, Jatrorrhizine, Berberine, Sephadex, Chemistry, Chemical constituents, Silica gel, Chromatography

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