2007•Chinese Journal of MycologyRequires access

Treatment effect of naftifine/ketoconazole cream to tinea pedis

Mingyu Zhang

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Abstract

Objective To observe the efficacy and safety of naftifine/ketoconazole cream in treatment of tinea pedis once daily.Methods Patients with tinea pedis were treated with naftifine/ketoconazole cream and were randomly divided into trial group(once daily) or control group(twice daily) for 4 weeks.The clinical follow-up was taken at the beginning and 2,4 weeks since the beginning of treatment and 2 weeks after stopping the treatment.Results The clinical and mycological effects of 2 groups had no statistically significant difference(P0.05) at the end of 4 weeks treatment and 2 weeks after stopping treatment.The mycological effects of 2 groups had statistically significant difference(P0.05)at 2 weeks treatment.Conclusions Naftifine/ketoconazole cream in treatment of tinea pedis once daily is efficient and safe.

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What this paper is about

Objective To observe the efficacy and safety of naftifine/ketoconazole cream in treatment of tinea pedis once daily.Methods Patients with tinea pedis were treated with naftifine/ketoconazole cream and were randomly divided into trial group(once daily) or control group(twice daily) for 4 weeks.The clinical follow-up was taken at the beginning and 2,4 weeks since the beginning of treatment and 2 weeks after stopping the treatment.Results The clinical and mycological effects of 2 groups had no statistically significant difference(P0.05) at the end of 4 weeks treatment and 2 weeks after stopping treatment.The mycological effects of 2 groups had statistically significant difference(P0.05)at 2 weeks treatment.Conclusions Naftifine/ketoconazole cream in treatment of tinea pedis once daily is efficient and safe.

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Available abstract

Objective To observe the efficacy and safety of naftifine/ketoconazole cream in treatment of tinea pedis once daily.Methods Patients with tinea pedis were treated with naftifine/ketoconazole cream and were randomly divided into trial group(once daily) or control group(twice daily) for 4 weeks.The clinical follow-up was taken at the beginning and 2,4 weeks since the beginning of treatment and 2 weeks after stopping the treatment.Results The clinical and mycological effects of 2 groups had no statistically significant difference(P0.05) at the end of 4 weeks treatment and 2 weeks after stopping treatment.The mycological effects of 2 groups had statistically significant difference(P0.05)at 2 weeks treatment.Conclusions Naftifine/ketoconazole cream in treatment of tinea pedis once daily is efficient and safe.

Key concepts: Ketoconazole, Medicine, Dermatology, Significant difference, Antifungal, Internal medicine

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