2010•The Chinese Journal of DermatovenereologyRequires access

Effect Observation of Keratotic Tinea Pedis Treatment with Naftifine Hydrochloride and Ketoconazole Cream Combine Two Chinese Medicine Preparations

Liao Lie

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Abstract

Objective To observe the clinical efficiency of naftifine hydrochloride and ketoconazole cream and traditional medicine solution compound in treating Keratotic Tinea Pedis.Methods 120 cases were divided into three groups(40 cases of each group)randomly.All three groups use Naftifine Hydrochloride and Ketoconazole Cream externally and external washing with warm water.Group B plus the Antifungal Granules,while group C plus the Xiang Lian Wai Xi Ye.Compared the curative effect and the fungus clearance rate after a period of treatment.Results Two weeks after stopping treatment,the fully recovery ratios of three groups were 34.21%,57.89% and 82.50% respectively.The effective ratios were 68.42%,89.47% and 97.50% respectively.The mycological effects were 89.47%,92.11% and 100.00% respectively.The fully recovery ratios and effective ratios of group C and group B were obviously prior to group A in two weeks after stopping treatment(all P0.05).The fully recovery ratio of group C was also prior to group B(P0.05).But there were no statistically significant differences between group C and group B of effective ratios (P0.05).The mycological effects of group C was obviously prior to group A in two weeks after stopping treatment(all P0.05).Conclusion The combination of naftifine hydrochloride and ketoconazole cream and traditional medicine solution compound in treating keratotic tinea pedis has good clinical efficiency and the safety.

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Objective To observe the clinical efficiency of naftifine hydrochloride and ketoconazole cream and traditional medicine solution compound in treating Keratotic Tinea Pedis.Methods 120 cases were divided into three groups(40 cases of each group)randomly.All three groups use Naftifine Hydrochloride and Ketoconazole Cream externally and external washing with warm water.Group B plus the Antifungal Granules,while group C plus the Xiang Lian Wai Xi Ye.Compared the curative effect and the fungus clearance rate after a period of treatment.Results Two weeks after stopping treatment,the fully recovery ratios of three groups were 34.21%,57.89% and 82.50% respectively.The effective ratios were 68.42%,89.47% and 97.50% respectively.The mycological effects were 89.47%,92.11% and 100.00% respectively.The fully recovery ratios and effective ratios of group C and group B were obviously prior to group A in two weeks after stopping treatment(all P0.05).The fully recovery ratio of group C was also prior to group B(P0.05).But there were no statistically significant differences between group C and group B of effective ratios (P0.05).The mycological effects of group C was obviously prior to group A in two weeks after stopping treatment(all P0.05).Conclusion The combination of naftifine hydrochloride and ketoconazole cream and traditional medicine solution compound in treating keratotic tinea pedis has good clinical efficiency and the safety.

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Available abstract

Objective To observe the clinical efficiency of naftifine hydrochloride and ketoconazole cream and traditional medicine solution compound in treating Keratotic Tinea Pedis.Methods 120 cases were divided into three groups(40 cases of each group)randomly.All three groups use Naftifine Hydrochloride and Ketoconazole Cream externally and external washing with warm water.Group B plus the Antifungal Granules,while group C plus the Xiang Lian Wai Xi Ye.Compared the curative effect and the fungus clearance rate after a period of treatment.Results Two weeks after stopping treatment,the fully recovery ratios of three groups were 34.21%,57.89% and 82.50% respectively.The effective ratios were 68.42%,89.47% and 97.50% respectively.The mycological effects were 89.47%,92.11% and 100.00% respectively.The fully recovery ratios and effective ratios of group C and group B were obviously prior to group A in two weeks after stopping treatment(all P0.05).The fully recovery ratio of group C was also prior to group B(P0.05).But there were no statistically significant differences between group C and group B of effective ratios (P0.05).The mycological effects of group C was obviously prior to group A in two weeks after stopping treatment(all P0.05).Conclusion The combination of naftifine hydrochloride and ketoconazole cream and traditional medicine solution compound in treating keratotic tinea pedis has good clinical efficiency and the safety.

Key concepts: Ketoconazole, Medicine, Antifungal, Group B, Dermatology, Traditional medicine, Internal medicine

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