The level and it's significance of ET-1 of urinary in neonates with asphyxia.
Wenbin Dong
Abstract
Wenbin Dong
Abstract
Objective: To explore the relationship between ET-1 of urinary and postasphyxial renal injury in neonatal asphyxia. Methosds: The level of ET-1 and β 2-MG in urinary were detected in neonates with asphyxia. Results: Compared with control, the level of ET-1 and β 2-MG were obviously increased in mild asphyxia group. In severe asphyxia group, the parameters above all were significantly increased compared with mild asphyxia group. and there were positive relationship between ET-1 and β 2-MG in all neonates with asphyxia. Conclusion: The level of ET-1 in urinary may be regarded as an indicator in evalulating the severity of asphyxia and postasphyxial renal injury in neonates.
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Objective: To explore the relationship between ET-1 of urinary and postasphyxial renal injury in neonatal asphyxia. Methosds: The level of ET-1 and β 2-MG in urinary were detected in neonates with asphyxia. Results: Compared with control, the level of ET-1 and β 2-MG were obviously increased in mild asphyxia group. In severe asphyxia group, the parameters above all were significantly increased compared with mild asphyxia group. and there were positive relationship between ET-1 and β 2-MG in all neonates with asphyxia. Conclusion: The level of ET-1 in urinary may be regarded as an indicator in evalulating the severity of asphyxia and postasphyxial renal injury in neonates.
Key concepts: Asphyxia, Medicine, Urinary system, Renal injury, Perinatal asphyxia, Anesthesia, Internal medicine, Renal function