Test of serum cardiac enzymes in 214 neonates with asphyxia and the clinical significance

Objective:To explore the clinical application value of activity test of serum cardiac enzymes in neonatal asphyxia.Methods:The serum levels of aspartate amino transferase(AST),creatine kinase(CK) and isoenzymes of creatine kinase(CK-MB) in 214 neonates with asphyxia were detected within 24 hours after birth.Results:The activity of cardiac enzymes in neonates with asphyxia increased,the serum levels of CK and CK-MB in severe asphyxia group were significantly higher than those in mild asphyxia group(P0.05).The total incidence of myocardial injury was 85.05%,there was no significant difference between mild asphyxia group(83.52%) and severe asphyxia group(92.11%)(P0.05).Conclusion:Neonatal asphyxia can induce myocardial injury,the increase of CK-MB activity is a early method to diagnose myocardial injury after asphyxia in neonates.