2011Chinese Journal of Clinical Rational Drug UseRequires access

Comparative effects of sufentanil and dezocine in artificial abortion

Mai Guang-lian

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Abstract

Objective To compare the clinical effects of f sufentanil and dezocine on artificial abortion.Methods 80 early pregnant women scheduled for painless artificial abortions were randomly divided into Sufentanil combined propofol group and Dezocine combined propofol group(40 in each).MAP,HR,RR and SpO2 were recorded immediately before anesthesia,during surgery,and after regained consciousness.The analgesic effects,respiratory depression,awake time after surgery VAS score and incidence of adverse reactions were observed.Results There was no significant difference in MAP,HR,RR and SpO2 between the two groups(P0.05).The indicators in Sufentanil combined propofol group were lower than that before anesthesia,and RR and SpO2 were lower than those in Dezocine combined propofol group,after regained consciousness,MAP,HR and SpO2 in Sufentanil combined propofol group were lower than those before anesthesia,there were no significant difference in all the indicators before anesthesia and after regained consciousness(P0.05).Total effective narcotic analgesic rate between Sufentanil+propofol group and to Dezocine+propofol group showed no significance(P0.05).Postoperative VAS score,the incidence rates of respiratory depression,nausea,vomiting and dizziness showed no significant difference between the two groups(P0.05),but awake time in Dezocine+propofol group was significantly shorter than that in Nepalese+propofol group(P0.05).Conclusion When combined with propofol as a regimen for artificial abortion,the analgesic effects of sufentanil and dezocine are similar,and the pregnant women emerge from anesthesia more rapidly in the case of the latter.

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Objective To compare the clinical effects of f sufentanil and dezocine on artificial abortion.Methods 80 early pregnant women scheduled for painless artificial abortions were randomly divided into Sufentanil combined propofol group and Dezocine combined propofol group(40 in each).MAP,HR,RR and SpO2 were recorded immediately before anesthesia,during surgery,and after regained consciousness.The analgesic effects,respiratory depression,awake time after surgery VAS score and incidence of adverse reactions were observed.Results There was no significant difference in MAP,HR,RR and SpO2 between the two groups(P0.05).The indicators in Sufentanil combined propofol group were lower than that before anesthesia,and RR and SpO2 were lower than those in Dezocine combined propofol group,after regained consciousness,MAP,HR and SpO2 in Sufentanil combined propofol group were lower than those before anesthesia,there were no significant difference in all the indicators before anesthesia and after regained consciousness(P0.05).Total effective narcotic analgesic rate between Sufentanil+propofol group and to Dezocine+propofol group showed no significance(P0.05).Postoperative VAS score,the incidence rates of respiratory depression,nausea,vomiting and dizziness showed no significant difference between the two groups(P0.05),but awake time in Dezocine+propofol group was significantly shorter than that in Nepalese+propofol group(P0.05).Conclusion When combined with propofol as a regimen for artificial abortion,the analgesic effects of sufentanil and dezocine are similar,and the pregnant women emerge from anesthesia more rapidly in the case of the latter.

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Available abstract

Objective To compare the clinical effects of f sufentanil and dezocine on artificial abortion.Methods 80 early pregnant women scheduled for painless artificial abortions were randomly divided into Sufentanil combined propofol group and Dezocine combined propofol group(40 in each).MAP,HR,RR and SpO2 were recorded immediately before anesthesia,during surgery,and after regained consciousness.The analgesic effects,respiratory depression,awake time after surgery VAS score and incidence of adverse reactions were observed.Results There was no significant difference in MAP,HR,RR and SpO2 between the two groups(P0.05).The indicators in Sufentanil combined propofol group were lower than that before anesthesia,and RR and SpO2 were lower than those in Dezocine combined propofol group,after regained consciousness,MAP,HR and SpO2 in Sufentanil combined propofol group were lower than those before anesthesia,there were no significant difference in all the indicators before anesthesia and after regained consciousness(P0.05).Total effective narcotic analgesic rate between Sufentanil+propofol group and to Dezocine+propofol group showed no significance(P0.05).Postoperative VAS score,the incidence rates of respiratory depression,nausea,vomiting and dizziness showed no significant difference between the two groups(P0.05),but awake time in Dezocine+propofol group was significantly shorter than that in Nepalese+propofol group(P0.05).Conclusion When combined with propofol as a regimen for artificial abortion,the analgesic effects of sufentanil and dezocine are similar,and the pregnant women emerge from anesthesia more rapidly in the case of the latter.

Key concepts: Dezocine, Medicine, Sufentanil, Propofol, Anesthesia, Vomiting, Nausea, Analgesic

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