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Measurements of NO,vWF and DD in Patients with Type 2 Diabetes Mellitus and Theirs Clinical Significance

Shen Wen

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Abstract

Objective To measure the plasma levels of NO, vWF and DD in patients with type 2 diabetes mellitus (DM) and to study its clinical significance. Methods ELISA method was used to detect the plasma levels of vWF and DD, nitric reductase methods for NO. Results The plasma vWF and DD levels of simple DM group were higher than that in the control group and the level of NO was lower than that in the control group. The plasma vWF level of DM with nephrotic syndrome was higher than that in the simple DM group. Conclusion The plasma levels of vWF, NO and DD reflect the structure and function alterations of blood vessels in patients with type 2 DM. The alteration of the plasma vWF levels would be a earlier prediction marker for diagnosis of nephrotic syndrome accompanied by type 2 DM.

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Objective To measure the plasma levels of NO, vWF and DD in patients with type 2 diabetes mellitus (DM) and to study its clinical significance. Methods ELISA method was used to detect the plasma levels of vWF and DD, nitric reductase methods for NO. Results The plasma vWF and DD levels of simple DM group were higher than that in the control group and the level of NO was lower than that in the control group. The plasma vWF level of DM with nephrotic syndrome was higher than that in the simple DM group. Conclusion The plasma levels of vWF, NO and DD reflect the structure and function alterations of blood vessels in patients with type 2 DM. The alteration of the plasma vWF levels would be a earlier prediction marker for diagnosis of nephrotic syndrome accompanied by type 2 DM.

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Available abstract

Objective To measure the plasma levels of NO, vWF and DD in patients with type 2 diabetes mellitus (DM) and to study its clinical significance. Methods ELISA method was used to detect the plasma levels of vWF and DD, nitric reductase methods for NO. Results The plasma vWF and DD levels of simple DM group were higher than that in the control group and the level of NO was lower than that in the control group. The plasma vWF level of DM with nephrotic syndrome was higher than that in the simple DM group. Conclusion The plasma levels of vWF, NO and DD reflect the structure and function alterations of blood vessels in patients with type 2 DM. The alteration of the plasma vWF levels would be a earlier prediction marker for diagnosis of nephrotic syndrome accompanied by type 2 DM.

Key concepts: Internal medicine, Endocrinology, Clinical significance, Type 2 Diabetes Mellitus, Medicine, Nephrotic syndrome, Diabetes mellitus

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