Clinical application of early detection of hs-CRP,D-D,vWF levels change in diabetes complications

Objective To study the relationship between hypersensitive C-reactive protein(hs-CRP) and complications in patients with type 2 diabetes,whether inflammation was involved in the occurrence of complications,and development;whether D-dimer(D-D),plasma vascular pseudo willebrand factor(vWF) reflected the vascular endothelial cell damage degree.Thus,to use it for mellitus and monitoring of vascular lesions in patients with early type 2 diabetes,and to provide theoretical basis for clinical.Methods Three hundred cases with different duration of diabetes patients were divided into three groups,each group had 100 cases,including diabetic vascular lesion group(DM 1),the merger of microvascular lesions with urinary micro protein group(DM 2),diabetes without complications(DM 3).Another 100 cases of patients without diabetes were chosen as normal control group(NC).the hs-CRP,D-D,vWF levels in the blood were detected.Results Compared with NC group,DM 1 and DM 2 and DM 3 group of hs-CRP,D-D and vWF levels increased significantly,the difference was statistically significant(P 0.01);compared with DM 3 group,DM 1 and DM 2 of hs-CRP,D-D and vWF levels increased significantly,the difference was statistically significant(P 0.01).Conclusion hs-CRP,D-D,and vWF concentrations are increased with the increace of combined vascular lesions.