ScholarLens Back to search
2013•Zhonghua zhongyiyao xuekanRequires access

Mechanism and Treatment Effect of Zhenwu Decoction on Adriamycin-induced Nephrosis in Rats

Liang Ransh

Open publisher page 0 citations

Abstract

Objective:To discuss the effect of Zhenwu Decoction on treating Adriamycin-induced nephrosis in rats and observe the changes of IL-6,TGF- B,levels.Method-.The SD rats were divided into normal control group,Adriamycin- induced nephrosis group,control group,Zhenwu Decoction group.10 days and 20 days after treatment,the 24 h urinary volume and urine protein,body weight,kidney weight index and the tissue levels of IL- 6,TGF- B,were tested.Results;The animals' 24 h urine protein,kidney weight index,IL- 6 and TGF-(},levels were higher than those in nomal control group(P0.05),and the body weight,24 h urinary volume were less than those in nomal group after the model succeeded.After treated with Zhenwu Decoction,the data was to some extent reversed(P0.05).Conclusion;lt has obvious effect that Zhenwu Decoction can treat Adriamycin- induced nephrosis in rats,this maybe have relation with the dicrease of IL-6 and TGF- p,levels.

About this research paper

What this paper is about

Objective:To discuss the effect of Zhenwu Decoction on treating Adriamycin-induced nephrosis in rats and observe the changes of IL-6,TGF- B,levels.Method-.The SD rats were divided into normal control group,Adriamycin- induced nephrosis group,control group,Zhenwu Decoction group.10 days and 20 days after treatment,the 24 h urinary volume and urine protein,body weight,kidney weight index and the tissue levels of IL- 6,TGF- B,were tested.Results;The animals' 24 h urine protein,kidney weight index,IL- 6 and TGF-(},levels were higher than those in nomal control group(P0.05),and the body weight,24 h urinary volume were less than those in nomal group after the model succeeded.After treated with Zhenwu Decoction,the data was to some extent reversed(P0.05).Conclusion;lt has obvious effect that Zhenwu Decoction can treat Adriamycin- induced nephrosis in rats,this maybe have relation with the dicrease of IL-6 and TGF- p,levels.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To discuss the effect of Zhenwu Decoction on treating Adriamycin-induced nephrosis in rats and observe the changes of IL-6,TGF- B,levels.Method-.The SD rats were divided into normal control group,Adriamycin- induced nephrosis group,control group,Zhenwu Decoction group.10 days and 20 days after treatment,the 24 h urinary volume and urine protein,body weight,kidney weight index and the tissue levels of IL- 6,TGF- B,were tested.Results;The animals' 24 h urine protein,kidney weight index,IL- 6 and TGF-(},levels were higher than those in nomal control group(P0.05),and the body weight,24 h urinary volume were less than those in nomal group after the model succeeded.After treated with Zhenwu Decoction,the data was to some extent reversed(P0.05).Conclusion;lt has obvious effect that Zhenwu Decoction can treat Adriamycin- induced nephrosis in rats,this maybe have relation with the dicrease of IL-6 and TGF- p,levels.

Key concepts: Decoction, Nephrosis, Urine, Medicine, Internal medicine, Endocrinology, Urinary system, Body weight

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Mechanism and Treatment Effect of Zhenwu Decoction on Adriamycin-induced Nephrosis in Rats — Research Paper | ScholarLens