Fast liquid chromatography for the resolution of chiral compounds
Scott R. Perrin
Abstract
Scott R. Perrin
Abstract
Abstract A Pirkle‐concept chiral stationary phase (CSP) derived from N‐(1‐naphthyl)leucine was evaluated for developing methods to reduce analysis times and investigating techniques in the rapid screening of a variety of chiral compounds over a given chiral selector. The effects of reduced column lengths and elevated temperatures were studied to shorten analysis times.
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Abstract A Pirkle‐concept chiral stationary phase (CSP) derived from N‐(1‐naphthyl)leucine was evaluated for developing methods to reduce analysis times and investigating techniques in the rapid screening of a variety of chiral compounds over a given chiral selector. The effects of reduced column lengths and elevated temperatures were studied to shorten analysis times.
Key concepts: Chemistry, Chiral stationary phase, Chiral derivatizing agent, Chiral column chromatography, Chromatography, Resolution (logic), Stationary phase, Chiral resolution