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CALCIUM UPTAKE IN IRRADIATED BONES

A Zuppinger, W Minder

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Abstract

The metabolism of calcium in irradiated bones was studied in rats following the administration of calcium45. One leg of each rat was irradiated and the uptake of calcium-45 compared with that in the unirradiated leg. One week after irradiation with 200 r the calcium uptake was lowered by 62% in the irradiated and 75% in the non-irradiated leg. One week later the non-irradiated leg had recovered, while the irradiated one showed the same damage, and during the next six weeks the uptake slowly dropped to 53%. Results indicate that this dose of radiation exerts an indirect temporary effect and a direct long-lasting damage to bone. (C.H.)

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What this paper is about

The metabolism of calcium in irradiated bones was studied in rats following the administration of calcium45. One leg of each rat was irradiated and the uptake of calcium-45 compared with that in the unirradiated leg. One week after irradiation with 200 r the calcium uptake was lowered by 62% in the irradiated and 75% in the non-irradiated leg. One week later the non-irradiated leg had recovered, while the irradiated one showed the same damage, and during the next six weeks the uptake slowly dropped to 53%. Results indicate that this dose of radiation exerts an indirect temporary effect and a direct long-lasting damage to bone. (C.H.)

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Available abstract

The metabolism of calcium in irradiated bones was studied in rats following the administration of calcium45. One leg of each rat was irradiated and the uptake of calcium-45 compared with that in the unirradiated leg. One week after irradiation with 200 r the calcium uptake was lowered by 62% in the irradiated and 75% in the non-irradiated leg. One week later the non-irradiated leg had recovered, while the irradiated one showed the same damage, and during the next six weeks the uptake slowly dropped to 53%. Results indicate that this dose of radiation exerts an indirect temporary effect and a direct long-lasting damage to bone. (C.H.)

Key concepts: Irradiation, Calcium, Chemistry, Radiochemistry, Internal medicine, Medicine, Nuclear physics, Physics

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