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THE EFFECT OF REPEATED GENERAL IRRADIATION BY SMALL DOSES OF X-RAY ON BONE TISSUE

N.A. Zhizhina

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Abstract

Changes in mineral metabolism were studied in the bones of white rats after repeated fractional irradiation by small doses (25 r) of x ray. Examination of mineral metabolism was carried out by determination of induced P/ sup 32/ and Ca/sup 45/ activity. Fractional irradiation of rats by small doses of x ray for 68 days (the total dose being 700 r) causes certain activation of the phosphorus calcium metabolism during 15 days following the final irradiation. Depression of metabolic processes in the bone tissue for 15 days after final irradiation was noted during numerous repeated irradiations of rats by small doses of x rays for 90 days (the total dose being 900 r). Changes revealed in the hard bone tissue (in the form of disturbances of the phosphorus calcium metabolism) are the indications of changes in the trophic processes of the bone tissue. (tr-auth)

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Changes in mineral metabolism were studied in the bones of white rats after repeated fractional irradiation by small doses (25 r) of x ray. Examination of mineral metabolism was carried out by determination of induced P/ sup 32/ and Ca/sup 45/ activity. Fractional irradiation of rats by small doses of x ray for 68 days (the total dose being 700 r) causes certain activation of the phosphorus calcium metabolism during 15 days following the final irradiation. Depression of metabolic processes in the bone tissue for 15 days after final irradiation was noted during numerous repeated irradiations of rats by small doses of x rays for 90 days (the total dose being 900 r). Changes revealed in the hard bone tissue (in the form of disturbances of the phosphorus calcium metabolism) are the indications of changes in the trophic processes of the bone tissue. (tr-auth)

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Available abstract

Changes in mineral metabolism were studied in the bones of white rats after repeated fractional irradiation by small doses (25 r) of x ray. Examination of mineral metabolism was carried out by determination of induced P/ sup 32/ and Ca/sup 45/ activity. Fractional irradiation of rats by small doses of x ray for 68 days (the total dose being 700 r) causes certain activation of the phosphorus calcium metabolism during 15 days following the final irradiation. Depression of metabolic processes in the bone tissue for 15 days after final irradiation was noted during numerous repeated irradiations of rats by small doses of x rays for 90 days (the total dose being 900 r). Changes revealed in the hard bone tissue (in the form of disturbances of the phosphorus calcium metabolism) are the indications of changes in the trophic processes of the bone tissue. (tr-auth)

Key concepts: Irradiation, Calcium, Metabolism, Bone tissue, Chemistry, Radiochemistry, Endocrinology, Phosphorus

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