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The Mutagenic Potential of 4-Nitrophenyl Isopropyl (Phenyl) Phosphinate, 4-Nitrophenyl Ethyl (Phenyl) Phosphinate, Phenyl 4-Nitropnenyl (Methyl) Phosphinate, 4-Nitrophenyl 2-Methoxphenyl Phosphinate, 4-Nitrophenyl 4-Nitrophenyl (Methyl) Phosphinate.
Leonard J. Sauers, Freddica R Pulliam, John T. Fruin
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Abstract
The mutagenic potential of 4-nitrophenyl isopropyl(phenyl)phosphinate (103B); 4-nitrophenyl ethyl(phenyl) phosphinate (113); phenyl 4-nitrophenyl(methyl)phosphinate (103A); 4-nitrophenyl 2-methoxypheny(methyl) phosphinate (36); and 4-nitrophenyl 4-nitrophenyl(methly)phosphinate (21) was assessed by using the Ames Salmonella/Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from 1 mg/plate to .00032 mg/plate. It was determined that none of the tested substances had mutagenic potential. (Author)