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The Mutagenic Potential of: 4-fluorophenyl methyl (phenyl) phosphinate, 4-nitrophenyl 4-trifluoromethylphenyl (methyl) phosphinate, 4-nitrophenyl 3-trifluoromethylphenyl (methyl) phosphinate, 4-methylsulfinylphenyl methyl (phenyl) phospinate.
Leonard J. Sauers, Freddica R Pulliam, John T. Fruin
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Abstract
The mutagenic potential of 4 fluorophenyl methy(phenyl)phosphinate (44*); 4-nitrophenyl 4-trifluoromethylphenyl(methyl)phosphinate (86*); 4-nitrophenyl 3-trifluoromethylphenyl(methyl)phosphinate (4*); 4-methylsulfinylphenyl methyl(phenyl)phosphinate (96*) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from 1 mg/plate to 3.2 x 10 to the -4 mg/plate. It was determined that none of the tested substances had mutagenic potential. (Author)