ESSENTIAL ARTERIAL HYPERTENSION WITH INSUFFICIENT DEGREE OF NOCTURNAL BLOOD PRESSURE REDUCTION: THE NEED OF CHRONOBIOLOGY APPROACH

A clinical case of chronotherapy in hypertension with insufficient degree of nocturnal blood pressure (BP) reduction was described. Patient M., average 24-h BP according to ambulatory blood pressure monitoring was160/98 mm Hg, systolic and diastolic blood pressure profile had non-dipper pattern. Taking into account individual circadian BP profile, the patient was recommended to take antihypertensive drug – lisinopril – at bedtime. As a result of this treatment, after 3 months the target levels and normalization of circadian rhythm of BP were achieved.