2022Pakistan Journal of Pharmaceutical SciencesOpen access

Death receptor-dependent apoptosis and cell cycle delay induced by bioymifi in human cervical cancer cells

Ahmet Altun, Zeynep Deniz Şahin İnan, Fatih Yulak

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Abstract

value (11.75μM) against HeLa cells. The cell cycle analysis demonstrated the increase of Bioymifi cured HeLa cells in the S phase. And also, 11.75µM of Bioymifi caused a significantly higher apoptotic effect compared to control. In addition, in vitro immunofluorescence experiments of this study represented that Bioymifi reduced Ki-67 localization in HeLa cells. Bioymifi has significantly anticancer actions in Human cervix cancer in vitro and can be combined with standard treatment.

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value (11.75μM) against HeLa cells. The cell cycle analysis demonstrated the increase of Bioymifi cured HeLa cells in the S phase. And also, 11.75µM of Bioymifi caused a significantly higher apoptotic effect compared to control. In addition, in vitro immunofluorescence experiments of this study represented that Bioymifi reduced Ki-67 localization in HeLa cells. Bioymifi has significantly anticancer actions in Human cervix cancer in vitro and can be combined with standard treatment.

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Available abstract

value (11.75μM) against HeLa cells. The cell cycle analysis demonstrated the increase of Bioymifi cured HeLa cells in the S phase. And also, 11.75µM of Bioymifi caused a significantly higher apoptotic effect compared to control. In addition, in vitro immunofluorescence experiments of this study represented that Bioymifi reduced Ki-67 localization in HeLa cells. Bioymifi has significantly anticancer actions in Human cervix cancer in vitro and can be combined with standard treatment.

Key concepts: HeLa, DAPI, Apoptosis, Flow cytometry, Cell cycle, Annexin, Cisplatin, Cancer cell

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Death receptor-dependent apoptosis and cell cycle delay induced by bioymifi in human cervical cancer cells — Research Paper | ScholarLens