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Quality Control

Lorne T. Kirby

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Abstract

Quality control (QC) is one aspect of quality assurance (QA). Quality assurance also includes (1) periodic laboratory audits by external specialists, (2) keeping up-to-date clearly-written protocols, (3) preparation of QA reports, (4) troubleshooting, (5) equipment maintenance and calibration, (6) methodology development, (7) personnel training, (8) continuing education, and (9) laboratory safety. To be assured of ongoing quality performance, laboratory accreditation is mandatory. The above aspects have been discussed throughout this text; however, because DNA profiling often involves legal considerations, details of QC are presented in this chapter. An extremely important report, Guidelines for a Quality Assurance Program for DNA Restriction Fragment Length Polymorphism Analysis , prepared by the Quality Assurance Subcommittee of TWGDAM, is included in Appendix I (Mudd 1989). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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What this paper is about

Quality control (QC) is one aspect of quality assurance (QA). Quality assurance also includes (1) periodic laboratory audits by external specialists, (2) keeping up-to-date clearly-written protocols, (3) preparation of QA reports, (4) troubleshooting, (5) equipment maintenance and calibration, (6) methodology development, (7) personnel training, (8) continuing education, and (9) laboratory safety. To be assured of ongoing quality performance, laboratory accreditation is mandatory. The above aspects have been discussed throughout this text; however, because DNA profiling often involves legal considerations, details of QC are presented in this chapter. An extremely important report, Guidelines for a Quality Assurance Program for DNA Restriction Fragment Length Polymorphism Analysis , prepared by the Quality Assurance Subcommittee of TWGDAM, is included in Appendix I (Mudd 1989). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Available abstract

Quality control (QC) is one aspect of quality assurance (QA). Quality assurance also includes (1) periodic laboratory audits by external specialists, (2) keeping up-to-date clearly-written protocols, (3) preparation of QA reports, (4) troubleshooting, (5) equipment maintenance and calibration, (6) methodology development, (7) personnel training, (8) continuing education, and (9) laboratory safety. To be assured of ongoing quality performance, laboratory accreditation is mandatory. The above aspects have been discussed throughout this text; however, because DNA profiling often involves legal considerations, details of QC are presented in this chapter. An extremely important report, Guidelines for a Quality Assurance Program for DNA Restriction Fragment Length Polymorphism Analysis , prepared by the Quality Assurance Subcommittee of TWGDAM, is included in Appendix I (Mudd 1989). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Key concepts: Troubleshooting, Quality assurance, Accreditation, QA/QC, Good laboratory practice, Audit, Quality audit, Quality control

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