Clinical analysis of montelukast sodium in the treatment of children with cough variant asthma

Objective To investigate the efficacy and safety of montelukast sodium in the treatment of children with cough variant asthma ( CVA) .Methods The 128 cases of children with CVA were randomly divided into two groups . 64 case in the control group were treated by taking procaterol hydrochloride orally for 7 days and stoped when cough was relieved.Budesonide aerosol inhalation was given at the same time .64 case in the observation group were treated by montelukast sodium chewable tablets , based on treatment in the control group .The clinical efficacy , safty and relapse rate within 3 months were evaluated after a course of treatment for 4 weeks in both groups .Results The total effective rate in the observation group was 93.75%, better than in the control group of 79.69%(P 0.05).3 months followed-up showed that the recurrence rate was lower in the observation group than in the con-trol group (P<0.05).Conclusion It is safe and effective to take montelukast as adjuvant therapy for children with CVA, with low recurrence rate , no serious adverse reactions , and good compliance .So, it is worthy of clinical applica-tion.