ScholarLens Back to search
2009•China Medical HeraldRequires access

Clinical therapeutic effect of Montelukast on cough variant asthma in children

Lin Xiaona

Open publisher page 0 citations

Abstract

Objective:To investigate the clinical effect of montelukast in treating and preventing children's cough variant asthma(CVA) and its safety.Methods:65 children with CVA were randomly divided into treatment group(n=32) and control group(n =33),received orally treatment of Montelukast and Ketotifen for 6 months respectively.Results:There were significant differences in time reaching clinically relieve and rate of recurrence that follow-up for 6 months,the treatment group was lower than control group(P0.01 and P0.05).The rate of peak expiratory flow rates(PEF) 90% in treatment group was higher than those of control group 3,6 months after treatment(P0.05).The treatment group had few side reaction occurred.Conclusion:Montelukast is safe and effective in treatment of children's CVA,it can improve lung function and reduce rate of recurrence.

About this research paper

What this paper is about

Objective:To investigate the clinical effect of montelukast in treating and preventing children's cough variant asthma(CVA) and its safety.Methods:65 children with CVA were randomly divided into treatment group(n=32) and control group(n =33),received orally treatment of Montelukast and Ketotifen for 6 months respectively.Results:There were significant differences in time reaching clinically relieve and rate of recurrence that follow-up for 6 months,the treatment group was lower than control group(P0.01 and P0.05).The rate of peak expiratory flow rates(PEF) 90% in treatment group was higher than those of control group 3,6 months after treatment(P0.05).The treatment group had few side reaction occurred.Conclusion:Montelukast is safe and effective in treatment of children's CVA,it can improve lung function and reduce rate of recurrence.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the clinical effect of montelukast in treating and preventing children's cough variant asthma(CVA) and its safety.Methods:65 children with CVA were randomly divided into treatment group(n=32) and control group(n =33),received orally treatment of Montelukast and Ketotifen for 6 months respectively.Results:There were significant differences in time reaching clinically relieve and rate of recurrence that follow-up for 6 months,the treatment group was lower than control group(P0.01 and P0.05).The rate of peak expiratory flow rates(PEF) 90% in treatment group was higher than those of control group 3,6 months after treatment(P0.05).The treatment group had few side reaction occurred.Conclusion:Montelukast is safe and effective in treatment of children's CVA,it can improve lung function and reduce rate of recurrence.

Key concepts: Medicine, Montelukast, Ketotifen, Asthma, Anesthesia, Lung function, Therapeutic effect, Pulmonary function testing

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical therapeutic effect of Montelukast on cough variant asthma in children — Research Paper | ScholarLens