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2000•Unpublished venueRequires access

Expression of Leukemia Inhibitory Factor in Human Decidua

YU Chiyan

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Abstract

Objective To study the expression and localization of leukemia inhibitory factor (LIF) in human first trimester decidual. Method By immunohistochemical analysis and in situ hybridization, the LIF mRNA and protein expressions were observed in 16 cases of human decidua. Results LIF mRNA and protein expressions were observed in all decidual specimens, the glanduar epithelium showed higher LIF expression than in stromal cells. Conclusion Expression of LIF in human decidua may contribute to embryo implantation, maintenance of placental functions and embryonic growth promation.

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What this paper is about

Objective To study the expression and localization of leukemia inhibitory factor (LIF) in human first trimester decidual. Method By immunohistochemical analysis and in situ hybridization, the LIF mRNA and protein expressions were observed in 16 cases of human decidua. Results LIF mRNA and protein expressions were observed in all decidual specimens, the glanduar epithelium showed higher LIF expression than in stromal cells. Conclusion Expression of LIF in human decidua may contribute to embryo implantation, maintenance of placental functions and embryonic growth promation.

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Available abstract

Objective To study the expression and localization of leukemia inhibitory factor (LIF) in human first trimester decidual. Method By immunohistochemical analysis and in situ hybridization, the LIF mRNA and protein expressions were observed in 16 cases of human decidua. Results LIF mRNA and protein expressions were observed in all decidual specimens, the glanduar epithelium showed higher LIF expression than in stromal cells. Conclusion Expression of LIF in human decidua may contribute to embryo implantation, maintenance of placental functions and embryonic growth promation.

Key concepts: Decidua, Leukemia inhibitory factor, In situ hybridization, Stromal cell, Immunohistochemistry, Decidual cells, Medicine, Embryo

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