Laboratory test of the resistance of Rattus tanezumi to warfarin and bromadiolone

Objective To determine the resistance of Rattus tanezumi to warfarin and bromadiolone in Changsha city where anticoagulants were not frequently used.Methods A non-selective feeding trial was conducted using 0.025% warfarin and 0.005% bromadiolone baits.Results After 18 days' application of 0.025% warfarin and 0.005% bromadiolone baits,dosage,the occurance rate of warfarin-resistant R.tanezumi was 43.48%(10/23),and that of bromadiolone-resistant ones was 21.21%(7/33).Conclusion Resistance of R.tanezumi to warfarine and bromadiolone still exists in Changsha city where anticoagulants were not frequently used in recent years.