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ANALYSE OF DRUG-SENSISTIVITY OF CLINICALLY ISOLATED PSEUDOMONAS AERUGINOSA

HU Xue-fei

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Abstract

[Objective] To analyze the drug-resistant situation of clinically isolated Pseudomonas Aeruginosa to the route antibiotics in our hospital from 2006s to 2007s, so as to offer evidence for clinical reasonable use antibiotics. [Methods] All clinical specimens isolated and cultured from patients were identified by using the automatic microorganism analyzer such as Microscan-autoscan-4 or VITEK-2, and bacteria’s drug susceptibility tests were performed using counterparts Panel. [Results] Pseudomonas Aeruginosa’s drug -resistance were severe to some antibiotics. The high level resistant drugs were Ticarcillin, Ticarcillin / Clavulanic Acid, Ceftizoxime, Ceftriaxone, Cefotaxime, Tetracycline, and Trimethoprim / Sulfamethoxazole. The low level resistant drugs were Piperacillin, Piperacillin / Tazobactam, Meropenem, Amikacin and Tobramycin. [Conclusion] Pseudomonas Aeruginosa’ drug-resistance is very high to many antibiotics so that we should select suitable antibiotics to cure Pseudomonas Aeruginosa infection according to drug susceptibility results to gain effective treatment and slow down the occurrence of the resistant strains.

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[Objective] To analyze the drug-resistant situation of clinically isolated Pseudomonas Aeruginosa to the route antibiotics in our hospital from 2006s to 2007s, so as to offer evidence for clinical reasonable use antibiotics. [Methods] All clinical specimens isolated and cultured from patients were identified by using the automatic microorganism analyzer such as Microscan-autoscan-4 or VITEK-2, and bacteria’s drug susceptibility tests were performed using counterparts Panel. [Results] Pseudomonas Aeruginosa’s drug -resistance were severe to some antibiotics. The high level resistant drugs were Ticarcillin, Ticarcillin / Clavulanic Acid, Ceftizoxime, Ceftriaxone, Cefotaxime, Tetracycline, and Trimethoprim / Sulfamethoxazole. The low level resistant drugs were Piperacillin, Piperacillin / Tazobactam, Meropenem, Amikacin and Tobramycin. [Conclusion] Pseudomonas Aeruginosa’ drug-resistance is very high to many antibiotics so that we should select suitable antibiotics to cure Pseudomonas Aeruginosa infection according to drug susceptibility results to gain effective treatment and slow down the occurrence of the resistant strains.

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Available abstract

[Objective] To analyze the drug-resistant situation of clinically isolated Pseudomonas Aeruginosa to the route antibiotics in our hospital from 2006s to 2007s, so as to offer evidence for clinical reasonable use antibiotics. [Methods] All clinical specimens isolated and cultured from patients were identified by using the automatic microorganism analyzer such as Microscan-autoscan-4 or VITEK-2, and bacteria’s drug susceptibility tests were performed using counterparts Panel. [Results] Pseudomonas Aeruginosa’s drug -resistance were severe to some antibiotics. The high level resistant drugs were Ticarcillin, Ticarcillin / Clavulanic Acid, Ceftizoxime, Ceftriaxone, Cefotaxime, Tetracycline, and Trimethoprim / Sulfamethoxazole. The low level resistant drugs were Piperacillin, Piperacillin / Tazobactam, Meropenem, Amikacin and Tobramycin. [Conclusion] Pseudomonas Aeruginosa’ drug-resistance is very high to many antibiotics so that we should select suitable antibiotics to cure Pseudomonas Aeruginosa infection according to drug susceptibility results to gain effective treatment and slow down the occurrence of the resistant strains.

Key concepts: Ticarcillin, Piperacillin, Pseudomonas aeruginosa, Tobramycin, Antibiotics, Microbiology, Tazobactam, Cefotaxime

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