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2014•Unpublished venueRequires access

The distribution and drug resistance of Pseudomonas aeruginosa

JI Yun-cha

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Abstract

Objective To analyze the drug-resistance of Pseudomonas aeruginosa in our hospital in recent 3 years, provide scientific basis for safe use of drugs,and contribute to the prevention and control of nosocomial infections. Methods Disc diffusion method was used to test the susceptibility of Pseudomonas aeruginosa isolated in our hospital during 2010 to 2012 to common used antibiotics. The results were analyzed with WHONET 5. 3 software in personal microcomputer. Results 369 strains of Pseudomonas aeruginosa were isolated. They showed no resistance to polymyxin B( PMB),low resistance rates( 6. 81% to 22. 73%) to imipenem,meropenem,cefoperazone / sulbactam,piperacillin / tazobactam and amikacin,and high resistance rates( 32. 47% to 73. 38%) to other antibacterial agents. Conclusion Pseudomonas aeruginosa is resistant to multiple antimicrobial drugs; Selection of antibiotics should be based on the detection results of the drug-resistance.

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What this paper is about

Objective To analyze the drug-resistance of Pseudomonas aeruginosa in our hospital in recent 3 years, provide scientific basis for safe use of drugs,and contribute to the prevention and control of nosocomial infections. Methods Disc diffusion method was used to test the susceptibility of Pseudomonas aeruginosa isolated in our hospital during 2010 to 2012 to common used antibiotics. The results were analyzed with WHONET 5. 3 software in personal microcomputer. Results 369 strains of Pseudomonas aeruginosa were isolated. They showed no resistance to polymyxin B( PMB),low resistance rates( 6. 81% to 22. 73%) to imipenem,meropenem,cefoperazone / sulbactam,piperacillin / tazobactam and amikacin,and high resistance rates( 32. 47% to 73. 38%) to other antibacterial agents. Conclusion Pseudomonas aeruginosa is resistant to multiple antimicrobial drugs; Selection of antibiotics should be based on the detection results of the drug-resistance.

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Available abstract

Objective To analyze the drug-resistance of Pseudomonas aeruginosa in our hospital in recent 3 years, provide scientific basis for safe use of drugs,and contribute to the prevention and control of nosocomial infections. Methods Disc diffusion method was used to test the susceptibility of Pseudomonas aeruginosa isolated in our hospital during 2010 to 2012 to common used antibiotics. The results were analyzed with WHONET 5. 3 software in personal microcomputer. Results 369 strains of Pseudomonas aeruginosa were isolated. They showed no resistance to polymyxin B( PMB),low resistance rates( 6. 81% to 22. 73%) to imipenem,meropenem,cefoperazone / sulbactam,piperacillin / tazobactam and amikacin,and high resistance rates( 32. 47% to 73. 38%) to other antibacterial agents. Conclusion Pseudomonas aeruginosa is resistant to multiple antimicrobial drugs; Selection of antibiotics should be based on the detection results of the drug-resistance.

Key concepts: Pseudomonas aeruginosa, Sulbactam, Cefoperazone, Meropenem, Piperacillin, Tazobactam, Amikacin, Imipenem

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