2012•Zhongguo redai yixueRequires access
Clinical distribution and drug resistance of Acinetobacter baumannii
Yang Jia
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Abstract
Objective To investigate the clinical distribution and drug resistance of Acinetobacter baumannii and offer assistance for treatment of nosocomial infection.Methods Totally 339 Acinetobacter baumannii strains were isolated from January 2009 to December 2010.Susceptibility of Acinetobacter baumannii to antimicrobials were tested by using Kirby-Bauer method.The data were analyzed with WHONET5.3 software according to CLSI2009 standard.Results The samples were mainly collected from respiratory tract(74.9%),the noisocomial infection of Acinelobacter baumannii was higher in ICU(28.9%).The resistance rate of Acinetobacter baumanoii to cefoperazone/sulbactem was reduced from 25.3% in 2009 to 18.3% in 2010,the resistance rate to minocycline was increased from 20.3% in 2009 to 37.7% in 2010,while to imipenem and meropenem were increased from 57.5% and 62.7% in 2009 to 66.5% and 70.7% in 2010.The resistance rate to other antimicrobials were all over 50.3%.Conclusion The resistance of Acinelobacter baumannii to antimicrobials shows a asecending trend,but is still susceptible to cefoperazone/sulbactem and minocycline.