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2010•Zhongguo redai yixueRequires access

Serological detections of syphilis

Xie Shi-ha

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Abstract

Aim To compare two kinds of serological approaches detecting Treponema pallidum antibody baesd on TPPA methods.Methods TRUST and ELISA were used to detect 883 serum specimens from STD outpationts.TPPA method was used to detect serum specimens with either TRUST positive or ELISA positive results.Results The sensitivity,the false positive rate and the missed detection rate of TRUST were 71.01% (245/345),8.92 %(24/269),28.99%(100/345),while the results of ELISA were 99.42%(343/345),0.58%(2/345)and 0.58(2/345)respectively.Compared with the results of TRUST, the results of the 3 index of ELISA showed statistically significant differences (P0.01).Comclusion ELISA is better than TRUST and is suitable for detection of antibody to Treponema pallidum in STD outpatients.

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Aim To compare two kinds of serological approaches detecting Treponema pallidum antibody baesd on TPPA methods.Methods TRUST and ELISA were used to detect 883 serum specimens from STD outpationts.TPPA method was used to detect serum specimens with either TRUST positive or ELISA positive results.Results The sensitivity,the false positive rate and the missed detection rate of TRUST were 71.01% (245/345),8.92 %(24/269),28.99%(100/345),while the results of ELISA were 99.42%(343/345),0.58%(2/345)and 0.58(2/345)respectively.Compared with the results of TRUST, the results of the 3 index of ELISA showed statistically significant differences (P0.01).Comclusion ELISA is better than TRUST and is suitable for detection of antibody to Treponema pallidum in STD outpatients.

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Available abstract

Aim To compare two kinds of serological approaches detecting Treponema pallidum antibody baesd on TPPA methods.Methods TRUST and ELISA were used to detect 883 serum specimens from STD outpationts.TPPA method was used to detect serum specimens with either TRUST positive or ELISA positive results.Results The sensitivity,the false positive rate and the missed detection rate of TRUST were 71.01% (245/345),8.92 %(24/269),28.99%(100/345),while the results of ELISA were 99.42%(343/345),0.58%(2/345)and 0.58(2/345)respectively.Compared with the results of TRUST, the results of the 3 index of ELISA showed statistically significant differences (P0.01).Comclusion ELISA is better than TRUST and is suitable for detection of antibody to Treponema pallidum in STD outpatients.

Key concepts: Treponema, Serology, Syphilis, Medicine, Antibody, Internal medicine, Immunology, Human immunodeficiency virus (HIV)

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