2011•Laboratory Medicine and ClinicRequires access
Comparison of the 3 approaches on detection of syphilis
Yuan Li
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Abstract
Objective To compare the specificity of three kinds of serological approaches on detecting treponema pallidum antibody and the clinical application values in clinic.Methods Three approaches including TRUST,TPPA,ELISA were used to detect 228 serum specimens.Results The sensitivities of the three approaches(TRUST,TPPA,ELISA) were 85.83%,98.33%,99.17%;The specificities of the three approaches were 95.37%,99.07%,98.15% respectively.The sensitivity and specificity of TRUST were lower than those of the TPPA(P0.05);The sensitivity and specificity of ELISA were not lower than those of the TPPA(P0.05);The sensitivity of TRUST was lower than that of the ELISA(P0.05),but the specificity of TRUST was not lower than that of the ELISA(P0.05).Conclusion It is suggested that TPPA and ELISA are the first choice on detecting syphilis antibody.