2009•Zhongguo fuyou baojianRequires access

Analysis on drug tolerance of klebsiella pneumoniae and detection of extended spectrum β-lactamase in hospital infection of pediatrics in Changchun

Yi Shi

Abstract

Objective:To explore the characteristics of drug tolerance of extended spectrumβ-lactamase (ESBLs) among klebsiella pneumoniae,provide a foundation for treatment.Methods:Drug tolerance of klebsiella pneumoniae and the strains producting ESBLs were monitored by disk agar diffusion method and double disc synergy test.Results:85 strains were isolated from 306 specimens,the ESBLs positive strains accounted for 31.8%;the drug resistance rate of ESBLs positive strains was higher than that of ESBLs negative strains,the former was highly sensitive to imipenem specifically.Conclusion:The detection rate of ESBLs among klebsiella pneumoniae in Changchun city is higher and multiple drug resistance is serious.

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Key concepts: Klebsiella pneumoniae, Medicine, Imipenem, Drug resistance, Microbiology, Klebsiella, Agar diffusion test, Drug