2007中国药理学报:英文版Requires access

Autophagy is involved in cytotoxic effects of crotoxin in human breast cancer cell line MCF-7 cells

Ci-hui, Yan, Yaping, Yang, Zhenghong, Liang Qin, Zhen-lun, Gu, Paul Paul, Reid, Zhongqin, Liang Liang

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Abstract

目的:在 deathof MCF-7 房间导致了 autophagy 调查 crotoxin ( CrTX )的角色, caspase-3-deficient ,人的乳癌房间 line.Methods :有 CrTX 的各种各样的剂量的有教养的 MCF-7 房间 weretreated ,从 SouthAmerican 响尾蛇的毒液孤立的 phospholipase A2 ( PLA2 ), CrTX 的 Crotalus durissus terrificus.The cytotoxicity 当面, caspase 禁止者的 andabsence 与甲基 thiazolyl tetrazolium ( MTT )和 lactatedehydrogenase ( LDH )被测量 aut 的漏 assays.The 激活

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目的:在 deathof MCF-7 房间导致了 autophagy 调查 crotoxin ( CrTX )的角色, caspase-3-deficient ,人的乳癌房间 line.Methods :有 CrTX 的各种各样的剂量的有教养的 MCF-7 房间 weretreated ,从 SouthAmerican 响尾蛇的毒液孤立的 phospholipase A2 ( PLA2 ), CrTX 的 Crotalus durissus terrificus.The cytotoxicity 当面, caspase 禁止者的 andabsence 与甲基 thiazolyl tetrazolium ( MTT )和 lactatedehydrogenase ( LDH )被测量 aut 的漏 assays.The 激活

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Available abstract

目的:在 deathof MCF-7 房间导致了 autophagy 调查 crotoxin ( CrTX )的角色, caspase-3-deficient ,人的乳癌房间 line.Methods :有 CrTX 的各种各样的剂量的有教养的 MCF-7 房间 weretreated ,从 SouthAmerican 响尾蛇的毒液孤立的 phospholipase A2 ( PLA2 ), CrTX 的 Crotalus durissus terrificus.The cytotoxicity 当面, caspase 禁止者的 andabsence 与甲基 thiazolyl tetrazolium ( MTT )和 lactatedehydrogenase ( LDH )被测量 aut 的漏 assays.The 激活

Key concepts: MCF-7, Autophagy, Cytotoxicity, Cytotoxic T cell, Cell culture, Human breast, Apoptosis, MTT assay

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