2020•Bioorganic ChemistryRequires access

Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities

Jiaoli Ding, Jing Liu, Zhipeng Zhang, Jie Guo, Maojun Cheng, Yang Wan, Rikang Wang, Yuanying Fang, Zhiyu Guan, Yi Jin, Sai‐Sai Xie

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Key concepts: HeLa, Chemistry, HDAC1, Histone deacetylase, Coumarin, Acetylation, HDAC6, Histone deacetylase inhibitor

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Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities — Research Paper | ScholarLens