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2017•European Journal of Medicinal ChemistryOpen access

The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity

Ahmed T. Negmeldin, Joseph R. Knoff, Mary Kay H. Pflum

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Key concepts: HDAC8, HDAC6, Vorinostat, Chemistry, Acetylation, HDAC1, Histone deacetylase, Selectivity

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