2011•European Journal of Medicinal ChemistryOpen access

Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors

Wei‐Jan Huang, Ching‐Chow Chen, Shi-Wei Chao, Chia-Chun Yu, Chen-Yui Yang, Jih‐Hwa Guh, Yun-Chieh Lin, Chiao-I Kuo, Ping Yang, Chung-I Chang

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Key concepts: Chemistry, HDAC8, Hydroxamic acid, Histone deacetylase inhibitor, HDAC1, Histone deacetylase, Gene isoform, Potency

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