Post-stroke depression early intervention on neurological rehabilitation

Objective Depression after stroke in patients with early intervention,observation of the neurological rehabilitation.Methods 66 patients in June 2008 ～ 2009 Shangqiu City in June admitted the First People's Hospital,patients with depression according to the wishes of patients divided into treatment group 36 cases ,30 cases of the control group.All cases were routine drug treatment and rehabilitation training.Antidepressant group were treated with fluoxetine 2 0 mg orally,1 time/d,for 4 weeks.All the patients before and after 4 weeks of treatment with Hamilton depression scale assessment of depression,applications Ba rthel index assessment activities of daily living,with neurological deficit scores of neurologic impairment evaluation.Results The total effective rate 83% (30/36),the control group was 73% (22/30),the difference was significant (P ＜0.01) ,treatment group after 4 weeks compared with neurological deficit score the control group significantly improved (P ＜ 0.01 ),after 4 weeks treatment group Hamilton Depression Rating Scale ( Ha mi ltiondepressionscale.H AMD) ≥ 17 points were 2 cases of depression was 5% (2/36) the control group 4 weeks after H AMD ≥ 17 points in 6 patients,depression was 20% (6/30),differences were also significant (P ＜ 0.01 ) treatment group,no obvious adverse reactions.Conclusion Early intervention can significantly improve depression in patients with acute stroke depressive symptoms,activities of daily living and to promote recovery of neurological function. Key words: Stroke; Depressive disorder; Fluoxetine; Rehabilitation exercise