2017•国际医药卫生导报Requires access
The clinical research of breast feeding security and the HBV-DNA test in serum, milk of hepatitis B virus carrying pregnant women
Liping Lü
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Abstract
Objective
To study the security of breast feeding in hepatitis B virus carrying pregnant women.
Methods
The venous blood, milk of 192 hepatitis B virus carrying pregnant women were collected, tested the HBV-DNA load in serum, milk, and followed the HBV carrying condition of babies who had been done standard immunization.
Results
The positive rate of HBV-DNA in serum, milk were the highest in HBeAg + HBeAg + HBcAb positive pregnant women, followed by HBsAg + HBeAb + HBcAb positive pregnant women, the lowest in HBsAg positive pregnant women. There was statistically significant difference in HBV-DNA positive rate in milk among three groups (χ2=5.99, P<0.05). There was statistically significant difference in HBsAg positive rate in babies’ serum between breast feeding group and artificial feeding group (χ2=6.33, P<0.05).
Conclusion
Complete progresses of mother-infant block of HBV in standard, meanwhile test serum, milk of pregnant women, breast feeding of HBV carrying mothers is safe if HBV-DNA load is in a certain range.
Key words:
Hepatitis B virus; Artificial feeding; Breast feeding; HBV-DNA load; Security