2003•Journal of Practical Obstetrics and GynecologyRequires access
The Relationship between HBV Infectious Status in Pregnant Women and Intrauterine Infection of Fetus
Zheng Tingdi
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Abstract
Objective: To study the relationship of hepatitis B virus (HBV) infectious status in pregnant women to intrauterine fetal infective rate. Methods: 79 pregnant women were detected HBV by ELISA. Maternal serum and cord blood were tested for HBV-DNA with fluorescence quantitative PCR (FQ-PCR). Results: The HBV-DNA-positive rate in maternal serum and cord blood in 47 pregnant women with positive HBsAg, HBeAg, and anti-HBc were 97.9% and 31.9%, respectively. The HBV-DNA-positive rate in maternal serum and cord blood in 32 pregnant women with positive HBsAg, anti-HBe, and anti-HBc were 9.4% and 0, respectively. There was a significant difference between two groups (P0.01). Conclusions: There is a relationship between the HBV infectious status and HBV-DNA-positive rate in pregnant women and intrauterine fetal infection.