Effects of nifedipine combined with trimetazidine on stable angina pectoris of coronary heart disease

Objective To investigate the effects of nifedipine combined with trimetazidine on blood biochemical indexes and electrocardiogram in patients with stable angina pectoris of coronary heart disease. Methods A total of 68 patients with stable angina pectoris of coronary heart disease treated in the Department of Cardiology in the 109th Hospital of Shanxi from July 2016 to June 2018 were selected for the study, and they were divided into the control group and the observation group according to the random number table method, with 34 cases in each group. The control group was treated with aspirin, isosorbide dinitrate, trimetazidine and other lipid-lowering, chest pain relieving treatment. The observation group was additionally given nifedipine on the basis of treatment in the control group. The curative effect was evaluated, the blood biochemical indexes and electrocardiogram condition in the two groups were measured before and after treatment, adverse reactions were recorded. Results The total effective rate(67.65%) in the control group was lower than that in the observation group(88.24%, P 0.05). Conclusions Nifedipine combined with trimetazidine in the treatment of stable angina pectoris of coronary heart disease can significantly improve the symptoms of angina pectoris and effectively regulate the body lipid balance, with good effects. Key words: Nifedipine; Trimetazidine; Stable angina pectoris of coronary heart disease; Clinical effects