The diagnostic value of serum IMA, cTnI and hs-CRP in early diagnosis for acute myocardial infarction

Objective To provide a reasonable clinical evidence and testing index for acute myocardial infarction (AMI) early diagnosis by investigating the levels of serum ischemia-modified album(IMA),cardiac troponin I(cTnI) and high-sensitivity C-reactive protein (hs-CRP) in patients with AMI.Methods 66 cases with AMI were divided into two groups by the time of starting attack chest pain to clinic,the time of 0-4h as E group (39 cases),4-8h as F group (27 cases),another 59 healthy persons in the control group were detected.Then collected serum samples from each case to detect the concentration of the IMA,cTnI and hs-CRP.Results The levels of serum IMA,cTnI and hs-CRP in E group were significantly higher than those in the control group( P ＜ 0.05 or P ＜ 0.001 ),in addition to the IMA level was higher than normal,cTnI and hs-CRP levels were in the normal range.The levels of serum IMA,cTnI and hs-CRP in F group were significantly higher than the levels of control group( P ＜0.05 ) and also above the normal.Conclusion IMA,cTnI and hs-CRP not only can be used as the effective index for AMI early diagnosis,but also help for early diagnosis.The results provide a reliable basis for disease treatment and condition development. Key words: Cardiac troponinⅠ; Ischemia modified albumin;  Myocardial infarction ; C-reactive protein