Acute exacerbation of bronchial asthmarisk factors of antibiotic

Objective Analysis of patients with acute exacerbation of bronchial asthma (asthma),antibiotic treatment of reference.Methods Select our department from July 2010 to July 2013 were treated in line with the requirements analysis in patients with acute exacerbation of bronchial asthma in 97 cases,all serum procalcitonin (PCT),and randomly divided into control group (46 cases) and treatment group (51 cases).Treatment on the same basis,the control group by the treating physician based on experience with antibiotics.Treatment group in PCT≥0.25 μg/L when the use of antibiotics,otherwise do not.In cases cured under the premise of the rate of antibiotics were compared.Record all cases of sputum into the subjects of traits,disease severity,body temperature,C-reactive protein (CRP) and peripheral blood leukocyte count (WBC) as possible risk factors for antibiotics,and in PCT≥0.25 μg/L as the standard antibiotics do correlation analysis between.Results Rate of antibiotic treatment group (47.1％) than the control group (80.4％),and the difference was statistically significant (P ＜0.05).Meanwhile,when the PCT ≥ 0.25 μg/L when compared with before the on set of increased sputumorcough yellow purulent sputum,clinical severityas the most important-acriticaldegree ofcorrelation (P ＜ 0.05).Conclusions Patients with acute exacerbation of bronchialasthma,increased sputumor cough than before the onset of yellowpurulent sputum,clinical severityas the most importantwhen youneed to use antibiotics criticaldegree.Only fever,orelevated CRP or elevated WBC which a factor must be applied when it is not in accordance with antibiotics. Key words: Procalcitonin; Bronchial asthma ;  Antibiotic