Clinical observation of the effects of combined FE enzymes in the treatment of residual infected burn wounds at late postburn stage

Objective To confiming the effect of combined FE combined enzymes in the treatment of residual infected burn wounds at late postburn stage.Methods Thirty patients with residual wounds at late postburn stage were enrolled in the study,and they were randomly divided into A(treated with combined FE combined enzymes)and B( treated with gentamicin)groups,with 15 patients in each group,several layers of gauze,either soaked with combined FE combined enzymes in A or gentmnicin in B group,were used to cover the residual wounds at late postbum stage once to twice a day.Bacterial culture from the burn wounds exudation before and after drug administration was done before the application of the agents.Susceptibility of the bacteria to antibiotics were identified.The healing time of the burn wounds was recorded,and also bepatia and renal functions of the patients were examined.Results Eighty-nine percent bacteria could be killed by FE combined enzymes after gauze with FE enzymes had been used for over 3 d.The wound healing time the residual wounds at late posthurn stage in A group was siginificandy shorter than that in B group.No adverse side-effects were observed in either group.Condusion Combined FE combined enzymes is safe and effective for the elimination of residual wounds at late postbum stage,and it is beneficial to control wound infection and promote the wound healing. Key words: Burns;  Infection;  Combined FE enzymes;  Residual wound