2018•Unpublished venueRequires access

Comparative observation of the clinical effect of immediate recovery of fluid resuscitation in traumatic shock and delayed resuscitation

Pan Wang, Yirui Cao, Jian Cheng, Da Li, Qiang Huang

Open publisher page 0 citations

Abstract

Objective To investigate the clinical value of immediate fluid resuscitation and delayed resuscitation in patients with traumatic shock. Methods The patients with traumatic shock treated in the Critical Care Medicine Department of People′s Hospital of Wenjiang District from March 2014 to March 2017 were selected.According to the number of admission cases, one hundred and twenty patients with traumatic shock were randomly divided into two groups, 60 cases in each group.The control group was given early immediate fluid resuscitation, the observation group was given delayed resuscitation, and the blood coagulation and blood routine indexes of the two groups were compared before and after the fluid resuscitation in the two groups, and the amount of fluid rehydration and the fatality rate in the two groups of patients with 1 h shock were observed, and the incidence rate of acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS) were compared. Results After treatment, the blood clotting and blood routine indexes of the two groups were improved (P<0.05), of which the thromboplastin time (PT) ((11.04±1.17) s), activated partial thromboplastin time (APTT) ((28.12±5.93)s)in the observation group in the observation group were lower than those of the control group( (15.12±1.26) s, (36.17±9.05) s) (t=-15.37, -9.81, P<0.05), platelet countPLT) ((146.92±16.85)×109/L) was higher than that of the control group ((114.18±10.69)×109/L )(t=-9.77, P<0.05), and the blood routine hemoglobin (Hb) ((112.21±9.46) g/L), and the base surplus(BE)((-5.30±2.45) mmol/L )were all higher than those of the control group ((92.95±11.20) g/L, (-8.27±3.53) mmol/L ) (t=-11.46, -8.99, P<0.05), blood lactic acid (BL) ((2.79±1.12) mmol/L ) was lower than that of the control group ((3.54±1.37) mmol/L) (t=-8.99, P<0.05). The volume of 1 h infusion of shock in the observation group ((569.96±187.34) ml ) was lower than that of the control group ((1 957.35±204.14) ml) (t=8.725, P<0.05). The incidence of ARDS (3.33% (2/60)), MOD(3.33% (2/60)) and fatality(1.67%(1/60))were lower than those of the control group(8.33%(5/60), 6.67%(4/60), 6.67%(4/60)(χ2=2.725, 3.214, 2.985, P<0.05). Conclusion The early stage of traumatic shock delayed fluid resuscitation is conducive to the protection of the blood coagulation function of patients, to improve blood indicators, to reduce the amount of 1 h infusion and to reduce the incidence of ARDS and MODS. Key words: Traumatic shock; Immediate fluid resuscitation; Delayed resuscitation; Clinical value

About this research paper

What this paper is about

Objective To investigate the clinical value of immediate fluid resuscitation and delayed resuscitation in patients with traumatic shock. Methods The patients with traumatic shock treated in the Critical Care Medicine Department of People′s Hospital of Wenjiang District from March 2014 to March 2017 were selected.According to the number of admission cases, one hundred and twenty patients with traumatic shock were randomly divided into two groups, 60 cases in each group.The control group was given early immediate fluid resuscitation, the observation group was given delayed resuscitation, and the blood coagulation and blood routine indexes of the two groups were compared before and after the fluid resuscitation in the two groups, and the amount of fluid rehydration and the fatality rate in the two groups of patients with 1 h shock were observed, and the incidence rate of acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS) were compared. Results After treatment, the blood clotting and blood routine indexes of the two groups were improved (P<0.05), of which the thromboplastin time (PT) ((11.04±1.17) s), activated partial thromboplastin time (APTT) ((28.12±5.93)s)in the observation group in the observation group were lower than those of the control group( (15.12±1.26) s, (36.17±9.05) s) (t=-15.37, -9.81, P<0.05), platelet countPLT) ((146.92±16.85)×109/L) was higher than that of the control group ((114.18±10.69)×109/L )(t=-9.77, P<0.05), and the blood routine hemoglobin (Hb) ((112.21±9.46) g/L), and the base surplus(BE)((-5.30±2.45) mmol/L )were all higher than those of the control group ((92.95±11.20) g/L, (-8.27±3.53) mmol/L ) (t=-11.46, -8.99, P<0.05), blood lactic acid (BL) ((2.79±1.12) mmol/L ) was lower than that of the control group ((3.54±1.37) mmol/L) (t=-8.99, P<0.05). The volume of 1 h infusion of shock in the observation group ((569.96±187.34) ml ) was lower than that of the control group ((1 957.35±204.14) ml) (t=8.725, P<0.05). The incidence of ARDS (3.33% (2/60)), MOD(3.33% (2/60)) and fatality(1.67%(1/60))were lower than those of the control group(8.33%(5/60), 6.67%(4/60), 6.67%(4/60)(χ2=2.725, 3.214, 2.985, P<0.05). Conclusion The early stage of traumatic shock delayed fluid resuscitation is conducive to the protection of the blood coagulation function of patients, to improve blood indicators, to reduce the amount of 1 h infusion and to reduce the incidence of ARDS and MODS. Key words: Traumatic shock; Immediate fluid resuscitation; Delayed resuscitation; Clinical value

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the clinical value of immediate fluid resuscitation and delayed resuscitation in patients with traumatic shock. Methods The patients with traumatic shock treated in the Critical Care Medicine Department of People′s Hospital of Wenjiang District from March 2014 to March 2017 were selected.According to the number of admission cases, one hundred and twenty patients with traumatic shock were randomly divided into two groups, 60 cases in each group.The control group was given early immediate fluid resuscitation, the observation group was given delayed resuscitation, and the blood coagulation and blood routine indexes of the two groups were compared before and after the fluid resuscitation in the two groups, and the amount of fluid rehydration and the fatality rate in the two groups of patients with 1 h shock were observed, and the incidence rate of acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS) were compared. Results After treatment, the blood clotting and blood routine indexes of the two groups were improved (P<0.05), of which the thromboplastin time (PT) ((11.04±1.17) s), activated partial thromboplastin time (APTT) ((28.12±5.93)s)in the observation group in the observation group were lower than those of the control group( (15.12±1.26) s, (36.17±9.05) s) (t=-15.37, -9.81, P<0.05), platelet countPLT) ((146.92±16.85)×109/L) was higher than that of the control group ((114.18±10.69)×109/L )(t=-9.77, P<0.05), and the blood routine hemoglobin (Hb) ((112.21±9.46) g/L), and the base surplus(BE)((-5.30±2.45) mmol/L )were all higher than those of the control group ((92.95±11.20) g/L, (-8.27±3.53) mmol/L ) (t=-11.46, -8.99, P<0.05), blood lactic acid (BL) ((2.79±1.12) mmol/L ) was lower than that of the control group ((3.54±1.37) mmol/L) (t=-8.99, P<0.05). The volume of 1 h infusion of shock in the observation group ((569.96±187.34) ml ) was lower than that of the control group ((1 957.35±204.14) ml) (t=8.725, P<0.05). The incidence of ARDS (3.33% (2/60)), MOD(3.33% (2/60)) and fatality(1.67%(1/60))were lower than those of the control group(8.33%(5/60), 6.67%(4/60), 6.67%(4/60)(χ2=2.725, 3.214, 2.985, P<0.05). Conclusion The early stage of traumatic shock delayed fluid resuscitation is conducive to the protection of the blood coagulation function of patients, to improve blood indicators, to reduce the amount of 1 h infusion and to reduce the incidence of ARDS and MODS. Key words: Traumatic shock; Immediate fluid resuscitation; Delayed resuscitation; Clinical value

Key concepts: Resuscitation, Medicine, Partial thromboplastin time, ARDS, Traumatic Shock, Anesthesia, Prothrombin time, Shock (circulatory)

Related papers

Back to paper searchBrowse research topicsOriginal source
Comparative observation of the clinical effect of immediate recovery of fluid resuscitation in traumatic shock and delayed resuscitation — Research Paper | ScholarLens