2014•Chinese Journal of General PracticeRequires access

Immediate versus delayed fluid resuscitation in early stage of traumatic shock

Lian Pin

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Abstract

Objective To investigate the effect of delayed fluid resuscitation in early treatment of traumatic shock. Methods Fifty-two patients with traumatic shock in our hospital were randomly divided into observation group and control group with 26 cases in each group. The patients in the control group received the immediate fluid resuscitation,while the observation group received the delayed fluid resuscitation. The prothrombin time( PT),activated partial thromboplastin time(APTT),hematocrit(HCT),blood lactate(BL),blood PH and base deficit(BD) of the patients in both groups before and after the fluid resuscitation were compared. The resuscitating fluid in the first hour of shock and the mortality were compared between the two groups. Results The differences of HCT,BL,PH and BD before and after the treatment in the observation group were not statistically significant(P 0. 05). The HCT in the control group after treatment was(16. 93 ±2. 07) %,significantly lower than that before the treatment(P 0. 05),but BL,PH and BD was not(P 0. 05). PT in 8cases and APTT in 8 cases in the observation group increased after the treatment,which was significantly less than those in the control group(P 0. 05). The resuscitating fluid in the first hour of shock of the observation group was(486 ± 291)ml,significantly less than the control group( P 0. 05). The mortality rate in the observation group was 15. 38%,which was not statistically significant as compared with the control group(P 0. 05). The incidence of complications of survival patients in the observation group was 18. 18%,and in the control group was 35. 29%. The incidence of complication of the observation group was lower than that of the control group,but the difference was not statistical significant( P 0. 05).Conclusion Delayed fluid resuscitation for early traumatic shock is conducive to the protection of coagulation function in patients. It can improve the hypoxic state of the organs and tissue,and increase the clinical success rate.

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Objective To investigate the effect of delayed fluid resuscitation in early treatment of traumatic shock. Methods Fifty-two patients with traumatic shock in our hospital were randomly divided into observation group and control group with 26 cases in each group. The patients in the control group received the immediate fluid resuscitation,while the observation group received the delayed fluid resuscitation. The prothrombin time( PT),activated partial thromboplastin time(APTT),hematocrit(HCT),blood lactate(BL),blood PH and base deficit(BD) of the patients in both groups before and after the fluid resuscitation were compared. The resuscitating fluid in the first hour of shock and the mortality were compared between the two groups. Results The differences of HCT,BL,PH and BD before and after the treatment in the observation group were not statistically significant(P 0. 05). The HCT in the control group after treatment was(16. 93 ±2. 07) %,significantly lower than that before the treatment(P 0. 05),but BL,PH and BD was not(P 0. 05). PT in 8cases and APTT in 8 cases in the observation group increased after the treatment,which was significantly less than those in the control group(P 0. 05). The resuscitating fluid in the first hour of shock of the observation group was(486 ± 291)ml,significantly less than the control group( P 0. 05). The mortality rate in the observation group was 15. 38%,which was not statistically significant as compared with the control group(P 0. 05). The incidence of complications of survival patients in the observation group was 18. 18%,and in the control group was 35. 29%. The incidence of complication of the observation group was lower than that of the control group,but the difference was not statistical significant( P 0. 05).Conclusion Delayed fluid resuscitation for early traumatic shock is conducive to the protection of coagulation function in patients. It can improve the hypoxic state of the organs and tissue,and increase the clinical success rate.

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Available abstract

Objective To investigate the effect of delayed fluid resuscitation in early treatment of traumatic shock. Methods Fifty-two patients with traumatic shock in our hospital were randomly divided into observation group and control group with 26 cases in each group. The patients in the control group received the immediate fluid resuscitation,while the observation group received the delayed fluid resuscitation. The prothrombin time( PT),activated partial thromboplastin time(APTT),hematocrit(HCT),blood lactate(BL),blood PH and base deficit(BD) of the patients in both groups before and after the fluid resuscitation were compared. The resuscitating fluid in the first hour of shock and the mortality were compared between the two groups. Results The differences of HCT,BL,PH and BD before and after the treatment in the observation group were not statistically significant(P 0. 05). The HCT in the control group after treatment was(16. 93 ±2. 07) %,significantly lower than that before the treatment(P 0. 05),but BL,PH and BD was not(P 0. 05). PT in 8cases and APTT in 8 cases in the observation group increased after the treatment,which was significantly less than those in the control group(P 0. 05). The resuscitating fluid in the first hour of shock of the observation group was(486 ± 291)ml,significantly less than the control group( P 0. 05). The mortality rate in the observation group was 15. 38%,which was not statistically significant as compared with the control group(P 0. 05). The incidence of complications of survival patients in the observation group was 18. 18%,and in the control group was 35. 29%. The incidence of complication of the observation group was lower than that of the control group,but the difference was not statistical significant( P 0. 05).Conclusion Delayed fluid resuscitation for early traumatic shock is conducive to the protection of coagulation function in patients. It can improve the hypoxic state of the organs and tissue,and increase the clinical success rate.

Key concepts: Medicine, Resuscitation, Partial thromboplastin time, Hematocrit, Shock (circulatory), Prothrombin time, Anesthesia, Coagulopathy

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